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TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma
BACKGROUND: Asian populations are more likely to develop acral melanoma (AM) than Caucasians. The high-dose interferon (HD-IFN) α-2b regimen is the main adjuvant treatment for AM. TERT encodes the catalytic subunit of telomerase reverse transcriptase, which plays an important role in melanoma. Frequ...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054280/ https://www.ncbi.nlm.nih.gov/pubmed/30046245 http://dx.doi.org/10.2147/OTT.S158239 |