TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma

BACKGROUND: Asian populations are more likely to develop acral melanoma (AM) than Caucasians. The high-dose interferon (HD-IFN) α-2b regimen is the main adjuvant treatment for AM. TERT encodes the catalytic subunit of telomerase reverse transcriptase, which plays an important role in melanoma. Frequ...

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Detalles Bibliográficos
Autores principales: Yu, Sifan, Xu, Tianxiao, Dai, Jie, Ma, Meng, Tang, Huan, Chi, Zhihong, Si, Lu, Cui, Chuanliang, Sheng, Xinan, Kong, Yan, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054280/
https://www.ncbi.nlm.nih.gov/pubmed/30046245
http://dx.doi.org/10.2147/OTT.S158239

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