Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A

Women gain weight and their diabetes risk increases as they transition through menopause; these changes can be partly reversed by hormone therapy. However, the underlying molecular mechanisms mediating these effects are unknown. A novel knock-in mouse line with the selective blockade of the membrane...

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Detalles Bibliográficos
Autores principales: Ueda, Kazutaka, Takimoto, Eiki, Lu, Qing, Liu, Pangyen, Fukuma, Nobuaki, Adachi, Yusuke, Suzuki, Ryo, Chou, Shengpu, Baur, Wendy, Aronovitz, Mark J., Greenberg, Andrew S., Komuro, Issei, Karas, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054435/
https://www.ncbi.nlm.nih.gov/pubmed/29764860
http://dx.doi.org/10.2337/db17-1342

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