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Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
Production of reactive oxygen species (ROS) is a key instigator of β-cell dysfunction in diabetes. The pleiotropic cytokine interleukin 6 (IL-6) has previously been linked to β-cell autophagy but has not been studied in the context of β-cell antioxidant response. We used a combination of animal mode...
Autores principales: | Marasco, Michelle R., Conteh, Abass M., Reissaus, Christopher A., Cupit, John E., Appleman, Evan M., Mirmira, Raghavendra G., Linnemann, Amelia K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054440/ https://www.ncbi.nlm.nih.gov/pubmed/29784660 http://dx.doi.org/10.2337/db17-1280 |
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