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Design and synthesis of novel oridonin analogues as potent anticancer agents
To identify anticancer agents with higher potency and lower toxicity, a series of oridonin derivatives with substituted benzene moieties at the C17 position were designed, synthesised, and evaluated for their antiproliferative properties. Most of the derivatives exhibited antiproliferative effects a...
Autores principales: | Shen, Qing-Kun, Chen, Zheng-Ai, Zhang, Hong-Jian, Li, Jia-Li, Liu, Chuan-Feng, Gong, Guo-Hua, Quan, Zhe-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054517/ https://www.ncbi.nlm.nih.gov/pubmed/29303372 http://dx.doi.org/10.1080/14756366.2017.1419219 |
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