Cargando…
Impaired spatial memory codes in a mouse model of Rett syndrome
The Mecp2(+/-) mouse model recapitulates many phenotypes of patients with Rett syndrome (RTT), including learning and memory deficits. It is unknown, however, how the disease state alters memory circuit functions in vivo in RTT mice. Here we recorded from hippocampal place cells, which are thought t...
Autores principales: | Kee, Sara E, Mou, Xiang, Zoghbi, Huda Y, Ji, Daoyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054527/ https://www.ncbi.nlm.nih.gov/pubmed/30028675 http://dx.doi.org/10.7554/eLife.31451 |
Ejemplares similares
-
Rigid firing sequences undermine spatial memory codes in a neurodegenerative mouse model
por: Cheng, Jingheng, et al.
Publicado: (2013) -
Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome
por: Ure, Kerstin, et al.
Publicado: (2016) -
Comparing Mouse and Rat Hippocampal Place Cell Activities and Firing Sequences in the Same Environments
por: Mou, Xiang, et al.
Publicado: (2018) -
Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice
por: Hao, Shuang, et al.
Publicado: (2015) -
Tetrode recording of rat CA1 place cells in an observational spatial working memory task
por: Mou, Xiang, et al.
Publicado: (2022)