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Contribution of three dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer

Hepcidin is a peptide hormone that negatively regulates iron efflux and plays an important role in controlling the growth of breast tumors. In patients with breast cancer, the combined expression of hepcidin and its membrane target, ferroportin, predict disease outcome. However, mechanisms that cont...

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Detalles Bibliográficos
Autores principales: Blanchette-Farra, Nicole, Kita, Daniel, Konstorum, Anna, Tesfay, Lia, Lemler, David, Hegde, Poornima, Claffey, Kevin P., Torti, Frank M., Torti, Suzy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054540/
https://www.ncbi.nlm.nih.gov/pubmed/29695834
http://dx.doi.org/10.1038/s41388-018-0243-y