Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment

Previously, we have succeeded in converting induced pluripotent stem cells (iPSCs) into cancer stem cells (CSCs) by treating the iPSCs with conditioned medium of Lewis lung carcinoma (LLC) cells. The converted CSCs, named miPS-LLCcm cells, exhibited the self-renewal, differentiation potential, and p...

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Detalles Bibliográficos
Autores principales: Oo, Aung Ko Ko, Calle, Anna Sanchez, Nair, Neha, Mahmud, Hafizah, Vaidyanath, Arun, Yamauchi, Junya, Khayrani, Aprilliana Cahya, Du, Juan, Alam, Md Jahangir, Seno, Akimasa, Mizutani, Akifumi, Murakami, Hiroshi, Iwasaki, Yoshiaki, Chen, Ling, Kasai, Tomonari, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054593/
https://www.ncbi.nlm.nih.gov/pubmed/29621663
http://dx.doi.org/10.1016/j.tranon.2018.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054593/
https://www.ncbi.nlm.nih.gov/pubmed/29621663
http://dx.doi.org/10.1016/j.tranon.2018.03.001

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