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Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging
Despite the continuous renewal and turnover of the small intestinal epithelium, the intestinal crypt maintains a ‘soccer ball-like’, alternating pattern of stem and Paneth cells at the base of the crypt. To study the robustness of the alternating pattern, we used intravital two-photon microscopy in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054609/ https://www.ncbi.nlm.nih.gov/pubmed/30030455 http://dx.doi.org/10.1038/s41598-018-29230-y |