Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging

Despite the continuous renewal and turnover of the small intestinal epithelium, the intestinal crypt maintains a ‘soccer ball-like’, alternating pattern of stem and Paneth cells at the base of the crypt. To study the robustness of the alternating pattern, we used intravital two-photon microscopy in...

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Detalles Bibliográficos
Autores principales: Choi, Jiahn, Rakhilin, Nikolai, Gadamsetty, Poornima, Joe, Daniel J., Tabrizian, Tahmineh, Lipkin, Steven M., Huffman, Derek M., Shen, Xiling, Nishimura, Nozomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054609/
https://www.ncbi.nlm.nih.gov/pubmed/30030455
http://dx.doi.org/10.1038/s41598-018-29230-y

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