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Evidence for excessive osteoclast activation in SIRT6 null mice

SIRT6 is a NAD-dependent histone 3 deacetylase. SIRT6 null mice have been reported suffering osteopenia. However, the role of SIRT6 in bone resorption is still not well understood. In this study, we focused on the role of SIRT6 in osteoclast. We performed histological analysis on the femur, spine, a...

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Detalles Bibliográficos
Autores principales:	Zhang, Demao, Jing, Junjun, Lou, Feng, Li, Ruimin, Ping, Yilin, Yu, Fanyuan, Wu, Fanzi, Yang, Xiao, Xu, Ruoshi, Li, Feifei, Wang, Ke, Bai, Mingru, Pi, Caixia, Xie, Jing, Zheng, Liwei, Ye, Ling, Zhou, Xuedong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054613/ https://www.ncbi.nlm.nih.gov/pubmed/30030453 http://dx.doi.org/10.1038/s41598-018-28716-z

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