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Intact glycosphingolipidomic analysis of the cell membrane during differentiation yields extensive glycan and lipid changes

Glycosphingolipids (GSLs) are found in cellular membranes of most organisms and play important roles in cell-cell recognition, signaling, growth, and adhesion, among others. A method based on nanoflow high performance liquid chromatography-chip-quadrupole-time-of-flight mass spectrometry (nanoHPLC C...

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Detalles Bibliográficos
Autores principales: Wong, Maurice, Xu, Gege, Park, Dayoung, Barboza, Mariana, Lebrilla, Carlito B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054638/
https://www.ncbi.nlm.nih.gov/pubmed/30030471
http://dx.doi.org/10.1038/s41598-018-29324-7