Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a

Induced neural stem cells (iNSCs) reprogrammed from somatic cells have great potentials in cell replacement therapies and in vitro modeling of neural diseases. Direct conversion of fibroblasts into iNSCs has been shown to depend on a couple of key neural progenitor transcription factors (TFs), raisi...

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Detalles Bibliográficos
Autores principales: Xiao, Dongchang, Liu, Xiaoning, Zhang, Min, Zou, Min, Deng, Qinqin, Sun, Dayu, Bian, Xuting, Cai, Yulong, Guo, Yanan, Liu, Shuting, Li, Shengguo, Shiang, Evelyn, Zhong, Hongyu, Cheng, Lin, Xu, Haiwei, Jin, Kangxin, Xiang, Mengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054649/
https://www.ncbi.nlm.nih.gov/pubmed/30030434
http://dx.doi.org/10.1038/s41467-018-05209-1

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