A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model

Chronic kidney disease (CKD) poses a formidable challenge for public healthcare worldwide as vast majority of patients with CKD are also at risk of accelerated cardiovascular disease and death. Renal fibrosis is the common manifestation of CKD that usually leads to end-stage renal disease although t...

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Detalles Bibliográficos
Autores principales: Yu, Xinyi, Xia, Yunfeng, Zeng, Liyi, Zhang, Xi, Chen, Liqun, Yan, Shujuan, Zhang, Ruyi, Zhao, Chen, Zeng, Zongyue, Shu, Yi, Huang, Shifeng, Lei, Jiayan, Yuan, Chengfu, Zhang, Linghuan, Feng, Yixiao, Liu, Wei, Huang, Bo, Zhang, Bo, Luo, Wenping, Wang, Xi, Zhang, Hongmei, Haydon, Rex C., Luu, Hue H., He, Tong-Chuan, Gan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054654/
https://www.ncbi.nlm.nih.gov/pubmed/30030497
http://dx.doi.org/10.1038/s41598-018-29417-3

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