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Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed

In this study, we used BovineSNP50 Genotyping BeadChip data to estimate the structure, putative ancestral origin as well as to identify regions with selective sweeps that may have had an important role in the adaptation to tropical conditions of the ‘Charolais de Cuba’ (CHCU) breed. According to a p...

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Autores principales: Rodriguez-Valera, Yoel, Renand, Gilles, Naves, Michel, Fonseca-Jiménez, Yidix, Moreno-Probance, Teresa Inés, Ramos-Onsins, Sebastian, Rocha, Dominique, Ramayo-Caldas, Yuliaxis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054659/
https://www.ncbi.nlm.nih.gov/pubmed/30030481
http://dx.doi.org/10.1038/s41598-018-29453-z
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author Rodriguez-Valera, Yoel
Renand, Gilles
Naves, Michel
Fonseca-Jiménez, Yidix
Moreno-Probance, Teresa Inés
Ramos-Onsins, Sebastian
Rocha, Dominique
Ramayo-Caldas, Yuliaxis
author_facet Rodriguez-Valera, Yoel
Renand, Gilles
Naves, Michel
Fonseca-Jiménez, Yidix
Moreno-Probance, Teresa Inés
Ramos-Onsins, Sebastian
Rocha, Dominique
Ramayo-Caldas, Yuliaxis
author_sort Rodriguez-Valera, Yoel
collection PubMed
description In this study, we used BovineSNP50 Genotyping BeadChip data to estimate the structure, putative ancestral origin as well as to identify regions with selective sweeps that may have had an important role in the adaptation to tropical conditions of the ‘Charolais de Cuba’ (CHCU) breed. According to a principal component analysis, CHCU samples cluster together with taurine breeds with an estimated 93% of taurus ancestral alleles. Despite the short period since importation, we detected differentiation (Fst = 0.049) between the French Charolaise (CHA) and CHCU. However, CHA breed was the closest breed to CHCU followed by other hybrids breed with a clear CHA origin. Linkage disequilibrium (r(2)) decay tends to be lower in CHCU compared to CHA probably due to a less intense artificial selection programs of CHCU. Signals of recent adaptation to tropical conditions between CHCU and CHA were identified. Genes mapping within those regions reflect different functions related to immunity, metabolic changes and heat tolerance (CHCU) and muscle development and meat quality (CHA) that may have had an important role in the phenotypic differentiation of these breeds. Further studies will expand our knowledge on the molecular basis of adaptation of cattle to tropical conditions and molecular process associated with meat quality traits.
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spelling pubmed-60546592018-07-23 Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed Rodriguez-Valera, Yoel Renand, Gilles Naves, Michel Fonseca-Jiménez, Yidix Moreno-Probance, Teresa Inés Ramos-Onsins, Sebastian Rocha, Dominique Ramayo-Caldas, Yuliaxis Sci Rep Article In this study, we used BovineSNP50 Genotyping BeadChip data to estimate the structure, putative ancestral origin as well as to identify regions with selective sweeps that may have had an important role in the adaptation to tropical conditions of the ‘Charolais de Cuba’ (CHCU) breed. According to a principal component analysis, CHCU samples cluster together with taurine breeds with an estimated 93% of taurus ancestral alleles. Despite the short period since importation, we detected differentiation (Fst = 0.049) between the French Charolaise (CHA) and CHCU. However, CHA breed was the closest breed to CHCU followed by other hybrids breed with a clear CHA origin. Linkage disequilibrium (r(2)) decay tends to be lower in CHCU compared to CHA probably due to a less intense artificial selection programs of CHCU. Signals of recent adaptation to tropical conditions between CHCU and CHA were identified. Genes mapping within those regions reflect different functions related to immunity, metabolic changes and heat tolerance (CHCU) and muscle development and meat quality (CHA) that may have had an important role in the phenotypic differentiation of these breeds. Further studies will expand our knowledge on the molecular basis of adaptation of cattle to tropical conditions and molecular process associated with meat quality traits. Nature Publishing Group UK 2018-07-20 /pmc/articles/PMC6054659/ /pubmed/30030481 http://dx.doi.org/10.1038/s41598-018-29453-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Rodriguez-Valera, Yoel
Renand, Gilles
Naves, Michel
Fonseca-Jiménez, Yidix
Moreno-Probance, Teresa Inés
Ramos-Onsins, Sebastian
Rocha, Dominique
Ramayo-Caldas, Yuliaxis
Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title_full Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title_fullStr Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title_full_unstemmed Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title_short Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
title_sort genetic diversity and selection signatures of the beef ‘charolais de cuba’ breed
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054659/
https://www.ncbi.nlm.nih.gov/pubmed/30030481
http://dx.doi.org/10.1038/s41598-018-29453-z
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