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CYP2C9 and OATP1B1 genetic polymorphisms affect the metabolism and transport of glimepiride and gliclazide

The therapeutic use of glimepiride and gliclazide shows substantial inter-individual variation in pharmacokinetics and pharmacodynamics in human populations, which might be caused by genetic differences among individuals. The aim of this study was to assess the effect of CYP2C9 and OATP1B1 genetic p...

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Detalles Bibliográficos
Autores principales:	Yang, Fayou, Xiong, Xiaomin, Liu, Yonghua, Zhang, Hong, Huang, Shibo, Xiong, Yuqing, Hu, Xiao, Xia, Chunhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054689/ https://www.ncbi.nlm.nih.gov/pubmed/30030468 http://dx.doi.org/10.1038/s41598-018-29351-4

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