Dexmedetomidine attenuates spinal cord ischemia–reperfusion injury through both anti-inflammation and anti-apoptosis mechanisms in rabbits

BACKGROUND: Dexmedetomidine (Dex) can improve neuronal viability and protect the spinal cord from ischemia–reperfusion (I/R) injury, but the underlying mechanisms are not fully understood. This study investigated the effects of dexmedetomidine on the toll-like receptor 4 (TLR4)-mediated nuclear fact...

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Detalles Bibliográficos
Autores principales: Sun, Zhixiang, Zhao, Tianyun, Lv, Shaojun, Gao, Ying, Masters, Joe, Weng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054716/
https://www.ncbi.nlm.nih.gov/pubmed/30031397
http://dx.doi.org/10.1186/s12967-018-1583-7

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