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In silico mutational analysis and identification of stability centers in human interleukin-4

Interleukin-4 (IL-4) is a multifunctional cytokine that plays a critical role in apoptosis, differentiation and proliferation. The intensity of IL4 response depends upon binding to its receptor, IL-4R. The therapeutic efficiency of interleukins can be increased by generating structural mutants havin...

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Detalles Bibliográficos
Autores principales: Saini, Sandeep, Jyoti-Thakur, Chander, Kumar, Varinder, Suhag, Akshay, Jakhar, Niharika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054777/
https://www.ncbi.nlm.nih.gov/pubmed/30046620
http://dx.doi.org/10.22099/mbrc.2018.28855.1310

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