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In silico mutational analysis and identification of stability centers in human interleukin-4

Interleukin-4 (IL-4) is a multifunctional cytokine that plays a critical role in apoptosis, differentiation and proliferation. The intensity of IL4 response depends upon binding to its receptor, IL-4R. The therapeutic efficiency of interleukins can be increased by generating structural mutants havin...

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Detalles Bibliográficos
Autores principales:	Saini, Sandeep, Jyoti-Thakur, Chander, Kumar, Varinder, Suhag, Akshay, Jakhar, Niharika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shiraz University 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054777/ https://www.ncbi.nlm.nih.gov/pubmed/30046620 http://dx.doi.org/10.22099/mbrc.2018.28855.1310

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