Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway

Caffeine has been reported to delay aging and protect aging-associated disorders in Caenorhabditis elegans. However, the effects of low concentration of caffeine and its analogs on lifespan are currently missing. Herein, we report that at much lower concentrations (as low as 10 μg/ml), caffeine exte...

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Detalles Bibliográficos
Autores principales: Du, Xiaocui, Guan, Yun, Huang, Qin, Lv, Ming, He, Xiaofang, Yan, Liang, Hayashi, Shuhei, Fang, Chongye, Wang, Xuanjun, Sheng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054938/
https://www.ncbi.nlm.nih.gov/pubmed/30061824
http://dx.doi.org/10.3389/fnagi.2018.00211

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