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Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn’s Disease

A recent randomized study of whipworm Trichuris suis ova (TSO) in ileal Crohn’s disease failed to demonstrate a clinical benefit compared to placebo after 12 weeks. Nonetheless, it has recently been shown that the spontaneous small intestinal inflammatory changes in Nod2(-/-) (Nucleotide-binding oli...

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Detalles Bibliográficos
Autores principales:	Jaeger, Simon U., Schaeffeler, Elke, Winter, Stefan, Tremmel, Roman, Schölmerich, Jürgen, Malek, Nisar, Stange, Eduard F., Schwab, Matthias, Wehkamp, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054957/ https://www.ncbi.nlm.nih.gov/pubmed/30061834 http://dx.doi.org/10.3389/fphar.2018.00764

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