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Fatty Acid-Induced Lipotoxicity in Pancreatic Beta-Cells During Development of Type 2 Diabetes

Type 2 diabetes is caused by chronic insulin resistance and progressive decline in beta-cell function. Optimal beta-cell function and mass is essential for glucose homeostasis and beta-cell impairment leads to the development of diabetes. Elevated levels of circulating fatty acids (FAs) and disturba...

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Detalles Bibliográficos
Autores principales:	Oh, Yoon S., Bae, Gong D., Baek, Dong J., Park, Eun-Young, Jun, Hee-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054968/ https://www.ncbi.nlm.nih.gov/pubmed/30061862 http://dx.doi.org/10.3389/fendo.2018.00384

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