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Concentration and Subclass Distribution of Anti-ADAMTS13 IgG Autoantibodies in Different Stages of Acquired Idiopathic Thrombotic Thrombocytopenic Purpura

BACKGROUND: The acquired form of idiopathic thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease, in which the underlying deficiency of the ADAMTS13 protease is caused by autoantibodies, predominantly of the IgG isotype. Certain HLA-DR-DQ haplotypes were associated with the risk of dev...

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Detalles Bibliográficos
Autores principales:	Sinkovits, György, Szilágyi, Ágnes, Farkas, Péter, Inotai, Dóra, Szilvási, Anikó, Tordai, Attila, Rázsó, Katalin, Réti, Marienn, Prohászka, Zoltán
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054987/ https://www.ncbi.nlm.nih.gov/pubmed/30061898 http://dx.doi.org/10.3389/fimmu.2018.01646

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