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Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer’s Disease Pathology and Shows Differential Expression in Transgenic Mice
There is increasing evidence that metabolic dysfunction plays an important role in Alzheimer’s disease (AD). Brain insulin resistance and subsequent impairment of insulin and insulin-like growth factor (IGF) signaling are associated with the neurodegenerative and clinical features of AD. Nevertheles...
Autores principales: | Bonham, Luke W., Geier, Ethan G., Steele, Natasha Z. R., Holland, Dominic, Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055061/ https://www.ncbi.nlm.nih.gov/pubmed/30061810 http://dx.doi.org/10.3389/fnins.2018.00476 |
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