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Chromatin organization by an interplay of loop extrusion and compartmental segregation

Mammalian chromatin is spatially organized at many scales showing two prominent features in interphase: (i) alternating regions (1–10 Mb) of active and inactive chromatin that spatially segregate into different compartments, and (ii) domains (<1 Mb), that is, regions that preferentially interact...

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Detalles Bibliográficos
Autores principales: Nuebler, Johannes, Fudenberg, Geoffrey, Imakaev, Maxim, Abdennur, Nezar, Mirny, Leonid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055145/
https://www.ncbi.nlm.nih.gov/pubmed/29967174
http://dx.doi.org/10.1073/pnas.1717730115

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