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Rsd balances (p)ppGpp level by stimulating the hydrolase activity of SpoT during carbon source downshift in Escherichia coli

Bacteria respond to nutritional stresses by changing the cellular concentration of the alarmone (p)ppGpp. This control mechanism, called the stringent response, depends on two enzymes, the (p)ppGpp synthetase RelA and the bifunctional (p)ppGpp synthetase/hydrolase SpoT in Escherichia coli and relate...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Woo, Park, Young-Ha, Seok, Yeong-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055147/
https://www.ncbi.nlm.nih.gov/pubmed/29915072
http://dx.doi.org/10.1073/pnas.1722514115