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Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation

The ability to control the activity of CRISPR-dCas9 with precise spatiotemporal resolution will enable tight genome regulation of user-defined endogenous genes for studying the dynamics of transcriptional regulation. Optogenetic devices with minimal phototoxicity and the capacity for deep tissue pen...

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Detalles Bibliográficos
Autores principales:	Shao, Jiawei, Wang, Meiyan, Yu, Guiling, Zhu, Sucheng, Yu, Yuanhuan, Heng, Boon Chin, Wu, Jiali, Ye, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055150/ https://www.ncbi.nlm.nih.gov/pubmed/29967137 http://dx.doi.org/10.1073/pnas.1802448115

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