Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception

N-acyl amino acids (NAAs) are a structurally diverse class of bioactive signaling lipids whose endogenous functions have largely remained uncharacterized. To clarify the physiologic roles of NAAs, we generated mice deficient in the circulating enzyme peptidase M20 domain-containing 1 (PM20D1). Globa...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Jonathan Z., Roche, Alexander M., Berdan, Charles A., Louie, Sharon M., Roberts, Amanda J., Svensson, Katrin J., Dou, Florence Y., Bateman, Leslie A., Mina, Amir I., Deng, Zhaoming, Jedrychowski, Mark P., Lin, Hua, Kamenecka, Theodore M., Asara, John M., Griffin, Patrick R., Banks, Alexander S., Nomura, Daniel K., Spiegelman, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055169/
https://www.ncbi.nlm.nih.gov/pubmed/29967167
http://dx.doi.org/10.1073/pnas.1803389115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055169/
https://www.ncbi.nlm.nih.gov/pubmed/29967167
http://dx.doi.org/10.1073/pnas.1803389115

Ejemplares similares