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Reactive Oxygen Species and p38MAPK Have a Role in the Smad2 Linker Region Phosphorylation Induced by TGF-β

BACKGROUND: Transforming growth factor-β (TGF-β) in addition to the C-terminal region can phosphorylate receptor-regulated Smads (R-Smads) in their linker region. The aim of the present study was to evaluate the role of signaling mediators such as NAD(P)H oxidases (reactive oxygen species [ROS] gene...

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Detalles Bibliográficos
Autores principales: Mehr, Reyhaneh Niayesh, Kheirollah, Alireza, Seif, Faezeh, Dayati, Parisa, Babaahmadi-Rezaei, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055211/
https://www.ncbi.nlm.nih.gov/pubmed/30046209

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