DNA polymerase ζ deficiency causes impaired wound healing and stress-induced skin pigmentation

DNA polymerase ζ (pol ζ) is well established as a specialized enzyme important for DNA damage tolerance, facilitating DNA synthesis past lesions caused by radiation or chemical damage. We report that disruption of Rev3l (encoding the catalytic subunit of pol ζ) in mouse epidermis leads to a defect i...

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Detalles Bibliográficos
Autores principales: Lange, Sabine S, Bhetawal, Sarita, Reh, Shelley, Powell, Katherine Leslie, Kusewitt, Donna F, Wood, Richard D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055517/
https://www.ncbi.nlm.nih.gov/pubmed/30046772
http://dx.doi.org/10.26508/lsa.201800048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055517/
https://www.ncbi.nlm.nih.gov/pubmed/30046772
http://dx.doi.org/10.26508/lsa.201800048

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