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Two years of sarilumab in patients with rheumatoid arthritis and an inadequate response to MTX: safety, efficacy and radiographic outcomes

OBJECTIVES: To examine 2-year safety, efficacy and radiographic outcomes of sarilumab in adults with RA and inadequate response to MTX (MTX-IR). METHODS: In the randomized, placebo-controlled MOBILITY trial, MTX-IR patients received subcutaneous sarilumab (150 or 200 mg) or placebo every 2 weeks (q2...

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Detalles Bibliográficos
Autores principales:	Genovese, Mark C, van Adelsberg, Janet, Fan, Chunpeng, Graham, Neil M H, van Hoogstraten, Hubert, Parrino, Janie, Mangan, Erin K, Spindler, Alberto, Huizinga, Tom W J, van der Heijde, Désirée
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055572/ https://www.ncbi.nlm.nih.gov/pubmed/29746672 http://dx.doi.org/10.1093/rheumatology/key121

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