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Rapid Aqueous Late‐Stage Radiolabelling of [GaF(3)(BnMe(2)‐tacn)] by (18)F/(19)F Isotopic Exchange: Towards New PET Imaging Probes

A simple and rapid method for (18)F radiolabelling of [GaF(3)(BnMe(2)‐tacn)] by (18)F/(19)F isotopic exchange is described. The use of MeCN/H(2)O or EtOH/H(2)O (75:25) and aqueous [(18)F]F(−) (up to 200 MBq) with heating (80 °C, 10 min) gave 66±4 % (18)F incorporation at a concentration of 268 nm, a...

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Detalles Bibliográficos
Autores principales:	Monzittu, Francesco M., Khan, Imtiaz, Levason, William, Luthra, Sajinder K., McRobbie, Graeme, Reid, Gillian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055623/ https://www.ncbi.nlm.nih.gov/pubmed/29659110 http://dx.doi.org/10.1002/anie.201802446

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