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Single and multiple dose evaluation of a novel MetAP2 inhibitor: Results of a randomized, double‐blind, placebo‐controlled clinical trial

AIMS: Methionine aminopeptidase 2 (MetAP2) inhibition has been shown to result in significant weight loss and improved glucose control. This Phase 1 clinical trial assessed the safety and tolerability, pharmacokinetics and preliminary efficacy of a novel MetAP2 inhibitor, ZGN‐1061. METHODS: This cli...

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Detalles Bibliográficos
Autores principales:	Malloy, Jaret, Zhuang, Dongliang, Kim, Terri, Inskeep, Phil, Kim, Dennis, Taylor, Kristin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055687/ https://www.ncbi.nlm.nih.gov/pubmed/29577550 http://dx.doi.org/10.1111/dom.13305

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