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Fluorofenidone inhibits UV‐A induced senescence in human dermal fibroblasts via the mammalian target of rapamycin‐dependent SIRT1 pathway

The aim of this study was to investigate the protective effect of fluorofenidone (5‐methyl‐1‐[3‐fluorophenyl]‐2‐[1H]‐pyridone, AKF‐PD) on ultraviolet (UV)‐A‐induced senescence in human dermal fibroblasts (HDF) and examine the mechanisms involved. HDF were treated with AKF‐PD. Senescence‐associated (...

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Detalles Bibliográficos
Autores principales:	Lei, Dan, Huang, Yingxue, Xie, Hongfu, Yi, Yuxin, Long, Juan, Lin, Shangqing, Huang, Chuchu, Jian, Dan, Li, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055727/ https://www.ncbi.nlm.nih.gov/pubmed/29726032 http://dx.doi.org/10.1111/1346-8138.14304

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