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αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer

Although mutational inactivation of E‐cadherin (CDH1) is the main driver of invasive lobular breast cancer (ILC), approximately 10–15% of all ILCs retain membrane‐localized E‐cadherin despite the presence of an apparent non‐cohesive and invasive lobular growth pattern. Given that ILC is dependent on...

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Detalles Bibliográficos
Autores principales: de Groot, Jolien S, Ratze, Max AK, van Amersfoort, Miranda, Eisemann, Tanja, Vlug, Eva J, Niklaas, Mijanou T, Chin, Suet‐Feung, Caldas, Carlos, van Diest, Paul J, Jonkers, Jos, de Rooij, Johan, Derksen, Patrick WB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055824/
https://www.ncbi.nlm.nih.gov/pubmed/29774524
http://dx.doi.org/10.1002/path.5099