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αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer
Although mutational inactivation of E‐cadherin (CDH1) is the main driver of invasive lobular breast cancer (ILC), approximately 10–15% of all ILCs retain membrane‐localized E‐cadherin despite the presence of an apparent non‐cohesive and invasive lobular growth pattern. Given that ILC is dependent on...
Autores principales: | de Groot, Jolien S, Ratze, Max AK, van Amersfoort, Miranda, Eisemann, Tanja, Vlug, Eva J, Niklaas, Mijanou T, Chin, Suet‐Feung, Caldas, Carlos, van Diest, Paul J, Jonkers, Jos, de Rooij, Johan, Derksen, Patrick WB |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055824/ https://www.ncbi.nlm.nih.gov/pubmed/29774524 http://dx.doi.org/10.1002/path.5099 |
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