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Quantification of cystine in human renal proximal tubule cells using liquid chromatography–tandem mass spectrometry
Nephropathic cystinosis is characterized by abnormal intralysosomal accumulation of cystine throughout the body, causing irreversible damage to various organs, particularly the kidneys. Cysteamine, the currently available treatment, can reduce lysosomal cystine and postpone disease progression. Howe...
Autores principales: | Jamalpoor, Amer, Sparidans, Rolf W., Pou Casellas, Carla, Rood, Johannes J.M., Joshi, Mansi, Masereeuw, Rosalinde, Janssen, Manoe J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055858/ https://www.ncbi.nlm.nih.gov/pubmed/29517154 http://dx.doi.org/10.1002/bmc.4238 |
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