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Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions
Bones at different anatomical locations vary dramatically in size. For example, human femurs are 20-fold longer than the phalanges in the fingers and toes. The mechanisms responsible for these size differences are poorly understood. Bone elongation occurs at the growth plates and advances rapidly in...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056026/ https://www.ncbi.nlm.nih.gov/pubmed/30036371 http://dx.doi.org/10.1371/journal.pbio.2005263 |