Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab

Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated meningococcal strains. We describe a case in which a nongroupable meningococcal strain, which rarely causes disease in healthy persons, caused fatal disease in an...

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Autores principales: Nolfi-Donegan, Deirdre, Konar, Monica, Vianzon, Vianca, MacNeil, Jessica, Cooper, James, Lurie, Perrianne, Sedivy, Judi, Wang, Xin, Granoff, Dan M., McNamara, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056112/
https://www.ncbi.nlm.nih.gov/pubmed/30015608
http://dx.doi.org/10.3201/eid2408.180228
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author Nolfi-Donegan, Deirdre
Konar, Monica
Vianzon, Vianca
MacNeil, Jessica
Cooper, James
Lurie, Perrianne
Sedivy, Judi
Wang, Xin
Granoff, Dan M.
McNamara, Lucy
author_facet Nolfi-Donegan, Deirdre
Konar, Monica
Vianzon, Vianca
MacNeil, Jessica
Cooper, James
Lurie, Perrianne
Sedivy, Judi
Wang, Xin
Granoff, Dan M.
McNamara, Lucy
author_sort Nolfi-Donegan, Deirdre
collection PubMed
description Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated meningococcal strains. We describe a case in which a nongroupable meningococcal strain, which rarely causes disease in healthy persons, caused fatal disease in an eculizumab recipient despite meningococcal vaccination.
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spelling pubmed-60561122018-08-01 Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab Nolfi-Donegan, Deirdre Konar, Monica Vianzon, Vianca MacNeil, Jessica Cooper, James Lurie, Perrianne Sedivy, Judi Wang, Xin Granoff, Dan M. McNamara, Lucy Emerg Infect Dis Dispatch Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated meningococcal strains. We describe a case in which a nongroupable meningococcal strain, which rarely causes disease in healthy persons, caused fatal disease in an eculizumab recipient despite meningococcal vaccination. Centers for Disease Control and Prevention 2018-08 /pmc/articles/PMC6056112/ /pubmed/30015608 http://dx.doi.org/10.3201/eid2408.180228 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Nolfi-Donegan, Deirdre
Konar, Monica
Vianzon, Vianca
MacNeil, Jessica
Cooper, James
Lurie, Perrianne
Sedivy, Judi
Wang, Xin
Granoff, Dan M.
McNamara, Lucy
Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title_full Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title_fullStr Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title_full_unstemmed Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title_short Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab
title_sort fatal nongroupable neisseria meningitidis disease in vaccinated patient receiving eculizumab
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056112/
https://www.ncbi.nlm.nih.gov/pubmed/30015608
http://dx.doi.org/10.3201/eid2408.180228
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