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Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia
We assessed the efficacy of standard 3-day courses of chloroquine and dihydroartemisinin/piperaquine against Plasmodium vivax malaria. Compared with chloroquine, dihydroartemisinin/piperaquine was faster in clearing asexual P. vivax parasites and blocking human-to-mosquito transmission. This drug co...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Centers for Disease Control and Prevention
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056113/ https://www.ncbi.nlm.nih.gov/pubmed/29798745 http://dx.doi.org/10.3201/eid2408.170768 |
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| author | Popovici, Jean Vantaux, Amelie Primault, Lyse Samreth, Reingsey Piv, Eak Por Bin, Sophalai Kim, Saorin Lek, Dysoley Serre, David Menard, Didier |
| author_facet | Popovici, Jean Vantaux, Amelie Primault, Lyse Samreth, Reingsey Piv, Eak Por Bin, Sophalai Kim, Saorin Lek, Dysoley Serre, David Menard, Didier |
| author_sort | Popovici, Jean |
| collection | PubMed |
| description | We assessed the efficacy of standard 3-day courses of chloroquine and dihydroartemisinin/piperaquine against Plasmodium vivax malaria. Compared with chloroquine, dihydroartemisinin/piperaquine was faster in clearing asexual P. vivax parasites and blocking human-to-mosquito transmission. This drug combination was also more effective in preventing potential recurrences for >2 months. |
| format | Online Article Text |
| id | pubmed-6056113 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Centers for Disease Control and Prevention |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60561132018-08-01 Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia Popovici, Jean Vantaux, Amelie Primault, Lyse Samreth, Reingsey Piv, Eak Por Bin, Sophalai Kim, Saorin Lek, Dysoley Serre, David Menard, Didier Emerg Infect Dis Dispatch We assessed the efficacy of standard 3-day courses of chloroquine and dihydroartemisinin/piperaquine against Plasmodium vivax malaria. Compared with chloroquine, dihydroartemisinin/piperaquine was faster in clearing asexual P. vivax parasites and blocking human-to-mosquito transmission. This drug combination was also more effective in preventing potential recurrences for >2 months. Centers for Disease Control and Prevention 2018-08 /pmc/articles/PMC6056113/ /pubmed/29798745 http://dx.doi.org/10.3201/eid2408.170768 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| spellingShingle | Dispatch Popovici, Jean Vantaux, Amelie Primault, Lyse Samreth, Reingsey Piv, Eak Por Bin, Sophalai Kim, Saorin Lek, Dysoley Serre, David Menard, Didier Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title | Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title_full | Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title_fullStr | Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title_full_unstemmed | Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title_short | Therapeutic and Transmission-Blocking
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia |
| title_sort | therapeutic and transmission-blocking
efficacy of dihydroartemisinin/piperaquine and chloroquine against plasmodium vivax malaria, cambodia |
| topic | Dispatch |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056113/ https://www.ncbi.nlm.nih.gov/pubmed/29798745 http://dx.doi.org/10.3201/eid2408.170768 |
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