Cryo-EM structure of the polycystin 2-l1 ion channel

We report the near atomic resolution (3.3 Å) of the human polycystic kidney disease 2-like 1 (polycystin 2-l1) ion channel. Encoded by PKD2L1, polycystin 2-l1 is a calcium and monovalent cation-permeant ion channel in primary cilia and plasma membranes. The related primary cilium-specific polycystin...

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Detalles Bibliográficos
Autores principales: Hulse, Raymond E, Li, Zongli, Huang, Rick K, Zhang, Jin, Clapham, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056229/
https://www.ncbi.nlm.nih.gov/pubmed/30004384
http://dx.doi.org/10.7554/eLife.36931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056229/
https://www.ncbi.nlm.nih.gov/pubmed/30004384
http://dx.doi.org/10.7554/eLife.36931

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