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Gating mechanisms during actin filament elongation by formins
Formins play an important role in the polymerization of unbranched actin filaments, and particular formins slow elongation by 5–95%. We studied the interactions between actin and the FH2 domains of formins Cdc12, Bni1 and mDia1 to understand the factors underlying their different rates of polymeriza...
Autores principales: | Aydin, Fikret, Courtemanche, Naomi, Pollard, Thomas D, Voth, Gregory A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056239/ https://www.ncbi.nlm.nih.gov/pubmed/30035712 http://dx.doi.org/10.7554/eLife.37342 |
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