Cargando…
Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patient...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università di Salerno
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056252/ https://www.ncbi.nlm.nih.gov/pubmed/30050874 |
_version_ | 1783341313511391232 |
---|---|
author | Foccillo, Antonio Aicale, Rocco Maffulli, Nicola |
author_facet | Foccillo, Antonio Aicale, Rocco Maffulli, Nicola |
author_sort | Foccillo, Antonio |
collection | PubMed |
description | Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patients of both sex were recruited, 20 with osteoarthritis of the knee, 29 with osteoarthritis of the hip, and 41 with a hip fracture. The levels of Vit D were measured twice: on admission and on the fourth day after surgery. In patients undergoing knee arthroplasty, the levels of Vit D were 16.85 ng/ml in the preoperative and 18.235 ng/ml in the postoperative period. In patients undergoing hip arthroplasty, we found levels <4.20 ng/ml for men, while in women 25.20 ng/ml pre-operatively and 22.8 ng/ml post-operatively. In patients with a hip fracture, men progressed from very low levels preoperatively (6.38 ng/ml) with post-operative levels of 18.44 ng /ml. Women exhibited a slight improvement from 12.24 ng/ml pre-operatively to 17.9 ng/ml postoperatively. Patients who are candidates for hip and knee arthroplasty and in hip fracture patients exhibit low Vit D levels. The activation of the inflammatory cascade may induce reduction of Vit D levels, and this fall is associated with impaired bone health. |
format | Online Article Text |
id | pubmed-6056252 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Università di Salerno |
record_format | MEDLINE/PubMed |
spelling | pubmed-60562522018-07-26 Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study Foccillo, Antonio Aicale, Rocco Maffulli, Nicola Transl Med UniSa Articles Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patients of both sex were recruited, 20 with osteoarthritis of the knee, 29 with osteoarthritis of the hip, and 41 with a hip fracture. The levels of Vit D were measured twice: on admission and on the fourth day after surgery. In patients undergoing knee arthroplasty, the levels of Vit D were 16.85 ng/ml in the preoperative and 18.235 ng/ml in the postoperative period. In patients undergoing hip arthroplasty, we found levels <4.20 ng/ml for men, while in women 25.20 ng/ml pre-operatively and 22.8 ng/ml post-operatively. In patients with a hip fracture, men progressed from very low levels preoperatively (6.38 ng/ml) with post-operative levels of 18.44 ng /ml. Women exhibited a slight improvement from 12.24 ng/ml pre-operatively to 17.9 ng/ml postoperatively. Patients who are candidates for hip and knee arthroplasty and in hip fracture patients exhibit low Vit D levels. The activation of the inflammatory cascade may induce reduction of Vit D levels, and this fall is associated with impaired bone health. Università di Salerno 2018-03-31 /pmc/articles/PMC6056252/ /pubmed/30050874 Text en http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Foccillo, Antonio Aicale, Rocco Maffulli, Nicola Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title | Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title_full | Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title_fullStr | Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title_full_unstemmed | Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title_short | Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study |
title_sort | elective orthopaedic and trauma patients in southern italy are vitamin d deficient. a pilot study |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056252/ https://www.ncbi.nlm.nih.gov/pubmed/30050874 |
work_keys_str_mv | AT foccilloantonio electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy AT aicalerocco electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy AT maffullinicola electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy |