Cargando…

Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study

Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Foccillo, Antonio, Aicale, Rocco, Maffulli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università di Salerno 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056252/
https://www.ncbi.nlm.nih.gov/pubmed/30050874
_version_ 1783341313511391232
author Foccillo, Antonio
Aicale, Rocco
Maffulli, Nicola
author_facet Foccillo, Antonio
Aicale, Rocco
Maffulli, Nicola
author_sort Foccillo, Antonio
collection PubMed
description Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patients of both sex were recruited, 20 with osteoarthritis of the knee, 29 with osteoarthritis of the hip, and 41 with a hip fracture. The levels of Vit D were measured twice: on admission and on the fourth day after surgery. In patients undergoing knee arthroplasty, the levels of Vit D were 16.85 ng/ml in the preoperative and 18.235 ng/ml in the postoperative period. In patients undergoing hip arthroplasty, we found levels <4.20 ng/ml for men, while in women 25.20 ng/ml pre-operatively and 22.8 ng/ml post-operatively. In patients with a hip fracture, men progressed from very low levels preoperatively (6.38 ng/ml) with post-operative levels of 18.44 ng /ml. Women exhibited a slight improvement from 12.24 ng/ml pre-operatively to 17.9 ng/ml postoperatively. Patients who are candidates for hip and knee arthroplasty and in hip fracture patients exhibit low Vit D levels. The activation of the inflammatory cascade may induce reduction of Vit D levels, and this fall is associated with impaired bone health.
format Online
Article
Text
id pubmed-6056252
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Università di Salerno
record_format MEDLINE/PubMed
spelling pubmed-60562522018-07-26 Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study Foccillo, Antonio Aicale, Rocco Maffulli, Nicola Transl Med UniSa Articles Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the hip and knee and in patients with proximal femur fracture. A total of 90 patients of both sex were recruited, 20 with osteoarthritis of the knee, 29 with osteoarthritis of the hip, and 41 with a hip fracture. The levels of Vit D were measured twice: on admission and on the fourth day after surgery. In patients undergoing knee arthroplasty, the levels of Vit D were 16.85 ng/ml in the preoperative and 18.235 ng/ml in the postoperative period. In patients undergoing hip arthroplasty, we found levels <4.20 ng/ml for men, while in women 25.20 ng/ml pre-operatively and 22.8 ng/ml post-operatively. In patients with a hip fracture, men progressed from very low levels preoperatively (6.38 ng/ml) with post-operative levels of 18.44 ng /ml. Women exhibited a slight improvement from 12.24 ng/ml pre-operatively to 17.9 ng/ml postoperatively. Patients who are candidates for hip and knee arthroplasty and in hip fracture patients exhibit low Vit D levels. The activation of the inflammatory cascade may induce reduction of Vit D levels, and this fall is associated with impaired bone health. Università di Salerno 2018-03-31 /pmc/articles/PMC6056252/ /pubmed/30050874 Text en http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Foccillo, Antonio
Aicale, Rocco
Maffulli, Nicola
Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title_full Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title_fullStr Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title_full_unstemmed Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title_short Elective Orthopaedic and Trauma Patients in Southern Italy are Vitamin D Deficient. A Pilot Study
title_sort elective orthopaedic and trauma patients in southern italy are vitamin d deficient. a pilot study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056252/
https://www.ncbi.nlm.nih.gov/pubmed/30050874
work_keys_str_mv AT foccilloantonio electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy
AT aicalerocco electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy
AT maffullinicola electiveorthopaedicandtraumapatientsinsouthernitalyarevitaminddeficientapilotstudy