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PAS Kinase deficiency alters the glucokinase function and hepatic metabolism

The liver controls metabolic homeostasis in response to fasting and refeeding periods. Glucokinase (GCK) adjusts hepatic glucose phosphorylation to blood glucose levels, acting as a glucose sensor. Our objective was to determine whether PAS kinase (PASK), a nutrient sensor, could be affecting the ex...

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Detalles Bibliográficos
Autores principales: Pérez-García, A., Dongil, P., Hurtado-Carneiro, V., Blazquez, E., Sanz, C., Alvarez, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056484/
https://www.ncbi.nlm.nih.gov/pubmed/30038292
http://dx.doi.org/10.1038/s41598-018-29234-8