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Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2
Long noncoding RNAs (lncRNAs) are emerging as key regulators of crucial cellular processes. However, the molecular mechanisms of many lncRNA functions remain uncharacterized. Sox2ot is an evolutionarily conserved lncRNA that transcriptionally overlaps the pluripotency gene Sox2, which maintains the...
Autores principales: | Knauss, Jennifer L., Miao, Nan, Kim, Seung-Nam, Nie, Yanzhen, Shi, Yuelin, Wu, Tao, Pinto, Hugo Borges, Donohoe, Mary E., Sun, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056501/ https://www.ncbi.nlm.nih.gov/pubmed/30038234 http://dx.doi.org/10.1038/s41419-018-0840-2 |
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