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Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis

The association between lower circulating adiponectin (APN) levels and the development of pancreatic cancer has been reported. However, the effect of APN on the growth and survival of pancreatic cancer cells remains elusive. Here, we investigate the effects of the anti-diabetic APN receptor (AdipoR)...

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Detalles Bibliográficos
Autores principales:	Akimoto, Miho, Maruyama, Riruke, Kawabata, Yasunari, Tajima, Yoshitsugu, Takenaga, Keizo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056513/ https://www.ncbi.nlm.nih.gov/pubmed/30038429 http://dx.doi.org/10.1038/s41419-018-0851-z

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