Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation

We previously reported that treatment with a JNK inhibitory peptide (11R-JNKI) prevents islet apoptosis and enhances the islet function in vivo. In the present study, we explored more efficient JNK inhibitors. The inhibition of the JNK activity by five types of deletion peptides in 11R-JNKI was inve...

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Detalles Bibliográficos
Autores principales: Noguchi, Hirofumi, Miyagi-Shiohira, Chika, Nakashima, Yoshiki, Ebi, Nana, Hamada, Eri, Tamaki, Yoshihito, Kuwae, Kazuho, Kobayashi, Naoya, Saitoh, Issei, Watanabe, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056537/
https://www.ncbi.nlm.nih.gov/pubmed/30038242
http://dx.doi.org/10.1038/s41598-018-29481-9

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