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METTL3 regulates WTAP protein homeostasis
The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation. In addition, WTAP is also a regulator of the nuclear co...
Autores principales: | Sorci, Melissa, Ianniello, Zaira, Cruciani, Sonia, Larivera, Simone, Ginistrelli, Lavinia Ceci, Capuano, Ernestina, Marchioni, Marcella, Fazi, Francesco, Fatica, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056540/ https://www.ncbi.nlm.nih.gov/pubmed/30038300 http://dx.doi.org/10.1038/s41419-018-0843-z |
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