A lincRNA-p21/miR-181 family feedback loop regulates microglial activation during systemic LPS- and MPTP- induced neuroinflammation

The role of microglial-mediated sustained neuroinflammation in the onset and progression of Parkinson’s disease (PD) is well established, but the mechanisms contributing to microglial activation remain unclear. LincRNA-p21, a well studied long intergenic noncoding RNA (lincRNA), plays pivotal roles...

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Detalles Bibliográficos
Autores principales: Ye, Yongyi, He, Xiaozheng, Lu, Fengfei, Mao, Hengxu, Zhu, Zhiyuan, Yao, Longping, Luo, Wanxian, Sun, Xiang, Wang, Baoyan, Qian, Chen, Zhang, Yizhou, Lu, Guohui, Zhang, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056543/
https://www.ncbi.nlm.nih.gov/pubmed/30038357
http://dx.doi.org/10.1038/s41419-018-0821-5

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