Cargando…
Sex-Specific Gene-by-Vitamin D Interactions Regulate Susceptibility to Central Nervous System Autoimmunity
Vitamin D3 (VitD) insufficiency is postulated to represent a major modifiable risk factor for multiple sclerosis (MS). While low VitD levels strongly correlate with higher MS risk in white populations, this is not the case for other ethnic groups, suggesting the existence of a genetic component. Mor...
Autores principales: | Krementsov, Dimitry N., Asarian, Loredana, Fang, Qian, McGill, Mahalia M., Teuscher, Cory |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056725/ https://www.ncbi.nlm.nih.gov/pubmed/30065723 http://dx.doi.org/10.3389/fimmu.2018.01622 |
Ejemplares similares
-
Sex differences in susceptibility to influenza A virus infection depend on host genotype
por: Sabikunnahar, Bristy, et al.
Publicado: (2022) -
p38 MAP Kinase Signaling in Microglia Plays a Sex-Specific Protective Role in CNS Autoimmunity and Regulates Microglial Transcriptional States
por: McGill, Mahalia M., et al.
Publicado: (2021) -
Identification of novel loci controlling inflammatory bowel disease susceptibility utilizing the genetic diversity of wild-derived mice
por: Lahue, Karolyn G., et al.
Publicado: (2020) -
Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity
por: Bearoff, Frank, et al.
Publicado: (2016) -
Identification of Genetic Determinants of the Sexual Dimorphism in CNS Autoimmunity
por: Bearoff, Frank, et al.
Publicado: (2015)