MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017

Characteristic magnetic resonance imaging (MRI) findings in patients with chronic kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus. We report 4 cases of infants with clinical, laboratory, and MRI findings of kernicterus in this case series. This is the firs...

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Autores principales: Assefa Neknek, Getachew, Woldemichael, Kindu, Moges, Ayalew, Zewdneh Solomon, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Neuroradiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056755/
https://www.ncbi.nlm.nih.gov/pubmed/30046365
http://dx.doi.org/10.1016/j.radcr.2018.03.018
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author Assefa Neknek, Getachew
Woldemichael, Kindu
Moges, Ayalew
Zewdneh Solomon, Daniel
author_facet Assefa Neknek, Getachew
Woldemichael, Kindu
Moges, Ayalew
Zewdneh Solomon, Daniel
author_sort Assefa Neknek, Getachew
collection PubMed
description Characteristic magnetic resonance imaging (MRI) findings in patients with chronic kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus. We report 4 cases of infants with clinical, laboratory, and MRI findings of kernicterus in this case series. This is the first MRI report of kernicterus in Ethiopia. Awareness of the disease is raised in this report, and the role of magnetic resonance in detecting signal abnormalities associated with kernicterus in the globus pallidi is underscored. We recommend MRI to be part of the investigation in neonates with jaundice.
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spelling pubmed-60567552018-07-25 MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017 Assefa Neknek, Getachew Woldemichael, Kindu Moges, Ayalew Zewdneh Solomon, Daniel Radiol Case Rep Neuroradiology Characteristic magnetic resonance imaging (MRI) findings in patients with chronic kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus. We report 4 cases of infants with clinical, laboratory, and MRI findings of kernicterus in this case series. This is the first MRI report of kernicterus in Ethiopia. Awareness of the disease is raised in this report, and the role of magnetic resonance in detecting signal abnormalities associated with kernicterus in the globus pallidi is underscored. We recommend MRI to be part of the investigation in neonates with jaundice. Elsevier 2018-04-16 /pmc/articles/PMC6056755/ /pubmed/30046365 http://dx.doi.org/10.1016/j.radcr.2018.03.018 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Neuroradiology
Assefa Neknek, Getachew
Woldemichael, Kindu
Moges, Ayalew
Zewdneh Solomon, Daniel
MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title_full MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title_fullStr MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title_full_unstemmed MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title_short MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017
title_sort mri of bilirubin encephalopathy (kernicterus): a case series of 4 patients from sub-saharan africa, may 2017
topic Neuroradiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056755/
https://www.ncbi.nlm.nih.gov/pubmed/30046365
http://dx.doi.org/10.1016/j.radcr.2018.03.018
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